Phenylglyoxylic acid (sodium)

Phenylglyoxylic acid sodium (Benzoylformic acid sodium) is a metabolite of ethylbenzene and styrene (EB/S) and can be used as a biomarker of exposure to EB/S in human. Phenylglyoxylic acid sodium can be used as drug intermediate for synthesis of antineoplastic compounds[1][2].

Product Specifications

CAS Number

[43165-51-1]

Product Name Alternative

Benzoylformic acid (sodium)

UNSPSC

12352005

Hazard Statement

H302, H312, H332

Target

Drug Intermediate; Endogenous Metabolite

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease; Others

Field of Research

Metabolic Disease; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/phenylglyoxylic-acid-sodium.html

Purity

99.92

Solubility

10 mM in DMSO

Smiles

O=C(C(C1=CC=CC=C1)=O)O[Na]

Molecular Formula

C8H5NaO3

Molecular Weight

172.12

Precautions

H302, H312, H332

References & Citations

[1]Capella KM, et al. Ethylbenzene and styrene exposure in the United States based on urinary mandelic acid and phenylglyoxylic acid: NHANES 2005-2006 and 2011-2012. Environ Res. 2019 Apr;171:101-110.|[2]Capella KM, et al. Ethylbenzene and styrene exposure in the United States based on urinary mandelic acid and phenylglyoxylic acid: NHANES 2005-2006 and 2011-2012. Environ Res. 2019 Apr;171:101-110.|[3]Jiang W, et al., Diversity of complexes based on p-nitrobenzoylhydrazide, benzoylformic acid and diorganotin halides or oxides self-assemble: Cytotoxicity, the induction of apoptosis in cancer cells and DNA-binding properties. Bioorg Chem. 2020 Jan;94:103402.|[4]Leont'eva L I, et al. Antiinflammatory activity of derivatives of phenylglyoxylic acid[J]. Pharmaceutical Chemistry Journal, 1993, 27 (3) : 195-197.