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IL-2R alpha/CD25, Cynomolgus (HEK293, Fc)

Selected Variant

HY-P76786

Size: 1 Each

IL-2R alpha (CD25) is an essential component of high-affinity IL-2 receptors. IL-2R alpha enhances binding of IL-2 to its receptor complex so that regulates T cell growth and other lymphoid functions[1][2]. IL-2R alpha/CD25 Protein, Cynomolgus (HEK293, Fc) is a recombinant cynomolgus IL-2R alpha protein with an hFc tag at the C-terminus and is expressed in HEK293 cells. It consists of 213 amino acids (M1-R213) .

Product Specifications

Product Name Alternative

IL-2R alpha/CD25 Protein, Cynomolgus (HEK293, Fc), Cynomolgus, HEK293

UNSPSC

12352202

Type

Recombinant Proteins

Assay Protocol

https://www.medchemexpress.com/cytokines/il-2r-alpha-cd25-protein-cynomolgus-hek293-fc.html

Molecular Formula

102123605 (Gene_ID) H6WS54 (E22-R213) (Accession)

Molecular Weight

Approximately 65 kDa, based on SDS-PAGE under reducing conditions.

References & Citations

[1]H.Asao. Interleukin-2. Reference Module in Biomedical Sciences. 2014. ISBN 9780128012383.|[2]Kim HP, et al. The basis for IL-2-induced IL-2 receptor alpha chain gene regulation: importance of two widely separated IL-2 response elements. Immunity. 2001 Jul;15 (1) :159-72.|[3]Bell CJ, et al. Sustained in vivo signaling by long-lived IL-2 induces prolonged increases of regulatory T cells. J Autoimmun. 2015 Jan;56:66-80.|[4]Chistiakov DA, et al. The crucial role of IL-2/IL-2RA-mediated immune regulation in the pathogenesis of type 1 diabetes, an evidence coming from genetic and animal model studies. Immunol Lett. 2008 Jun 15;118 (1) :1-5.

Shipping Conditions

Dry ice.

Scientific Category

Recombinant Proteins

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