MMP-8 inhibitor-1

MMP-8 inhibitor-1 (compound 21), a hydroxamic acid derivative, is a potent MMP-8 inhibitor without significant oral bioavailability[1].

Product Specifications

CAS Number

[236403-25-1]

Product Name Alternative

MMP8-I

UNSPSC

12352005

Target

MMP

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/mmp-8-inhibitor-1.html

Purity

99.70

Solubility

DMSO : 100 mg/mL (ultrasonic; warming)

Smiles

O=S(N1[C@H](CC2=CC=CC=C2C1)C(NO)=O)(C3=CC=C(C=C3)OC)=O

Molecular Formula

C17H18N2O5S

Molecular Weight

362.40

References & Citations

[1]Matter H, et al. Tetrahydroisoquinoline-3-carboxylate based matrix-metalloproteinase inhibitors: design, synthesis and structure-activity relationship. Bioorg Med Chem. 2002 Nov;10 (11) :3529-44.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C (Powder, sealed storage, away from moisture)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

MMP-8

Available Sizes

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