MMP-8 inhibitor-1
MMP-8 inhibitor-1 (compound 21), a hydroxamic acid derivative, is a potent MMP-8 inhibitor without significant oral bioavailability[1].
Product Specifications
CAS Number
[236403-25-1]
Product Name Alternative
MMP8-I
UNSPSC
12352005
Target
MMP
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/mmp-8-inhibitor-1.html
Purity
99.70
Solubility
DMSO : 100 mg/mL (ultrasonic; warming)
Smiles
O=S(N1[C@H](CC2=CC=CC=C2C1)C(NO)=O)(C3=CC=C(C=C3)OC)=O
Molecular Formula
C17H18N2O5S
Molecular Weight
362.40
References & Citations
[1]Matter H, et al. Tetrahydroisoquinoline-3-carboxylate based matrix-metalloproteinase inhibitors: design, synthesis and structure-activity relationship. Bioorg Med Chem. 2002 Nov;10 (11) :3529-44.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
MMP-8
Available Sizes
Curated Selection
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