Meranzin
Product Specifications
UNSPSC Description
Meranzin is an absorbed bioactive compound from the Traditional Chinese Medicine (TCM) Chaihu-Shugan-San (CSS). Meranzin, isolated from leaves of Murraya exotica L., regulates the shared alpha 2-adrenoceptor and involves the AMPA-ERK1/2–BDNF signaling pathway. Meranzin has the potential for the prevention of the comorbidity of atherosclerosis and depression[1][2].
Target Antigen
Adrenergic Receptor
Type
Natural Products
Related Pathways
GPCR/G Protein;Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/meranzin.html
Purity
98.0
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
COC1=CC=C(C=C2)C(OC2=O)=C1C[C@H](O3)C3(C)C
Molecular Weight
260.29
References & Citations
[1]Lan Li, et al. Chaihu-Shugan-San and Absorbed Meranzin Hydrate Induce Anti-Atherosclerosis and Behavioral Improvements in High-Fat Diet ApoE -/- Mice via Anti-Inflammatory and BDNF-TrkB Pathway. Biomed Pharmacother. 2019 Jul;115:108893.|[2]Rongwei Yan, et al. Preparative Isolation and Purification of Hainanmurpanin, Meranzin, and Phebalosin From Leaves of Murraya Exotica L. Using Supercritical Fluid Extraction Combined With Consecutive High-Speed Countercurrent Chromatography. J Sep Sci. 2018 May;41(9):2092-2101.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-N3298/Meranzin-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-N3298/Meranzin-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
23971-42-8
Available Sizes
Curated Selection
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