OADS

OADS is a Chloride channel antiporter (ClC-ec1) inhibitor (IC50: 29 μM) . OADS specifically inhibits the ClC-ec1 antiporter but not the ClC-1 channel. OADS can be used for research of osteoporosis and neurodegenerative and cardiovascular diseases[1].

Product Specifications

CAS Number

[5970-15-0]

UNSPSC

12352005

Target

Chloride Channel

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel

Field of Research

Neurological Disease; Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/oads.html

Purity

98.25

Smiles

O=S(C1=CC(NC(CCCCCCC)=O)=CC=C1/C=C/C2=CC=C(NC(CCCCCCC)=O)C=C2S(=O)(O)=O)(O)=O

Molecular Formula

C30H42N2O8S2

Molecular Weight

622.79

References & Citations

[1]Howery AE, et al. A designed inhibitor of a CLC antiporter blocks function through a unique binding mode. Chem Biol. 2012 Nov 21;19 (11) :1460-70.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

Phase 4

Available Sizes

Curated Selection

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