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Human/Mouse BMP-2 Protein

Bone morphogenetic protein-2 (BMP-2) is a kind of bone growth regulator, belonging to protein transforming growth factor-β (TGF-β) superfamily. BMP-2 protein is involved in hedgehog pathway, TGF-β signaling pathway and cytokine-cytokine receptor interaction. BMP-2 and BMP-7 are osteogenic BMP, which have been proved to be effective in inducing osteoblast differentiation in many cell types. The active form of BMP-2 can be composed of dimers of two identical proteins or heterodimers of two related bone morphogenetic proteins.

Product Specifications

Background

Bone morphogenetic protein-2 (BMP-2) is a kind of bone growth regulator, belonging to protein transforming growth factor-β (TGF-β) superfamily. BMP-2 protein is involved in hedgehog pathway, TGF-β signaling pathway and cytokine-cytokine receptor interaction. BMP-2 and BMP-7 are osteogenic BMP, which have been proved to be effective in inducing osteoblast differentiation in many cell types. The active form of BMP-2 can be composed of dimers of two identical proteins or heterodimers of two related bone morphogenetic proteins.

Product Name Alternative

BMP2; BMP2A; Bone morphogenetic protein 2; BMP-2; Bone morphogenetic protein 2A; BMP-2A

Gene ID

12156

Accession Number

P12643

Tag

BMP-2

Type

Cytokines and proteins

Applications

No tag

Purity

> 95 % as determined by SDS-PAGE

Activity

Testing in progress

Molecular Weight

13 kDa

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Features & Benefits

Endotoxin: Please contact us for more information.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Lyophilized Human/Mouse BMP-2 protein product should be stored desiccated below -20°C. Upon reconstitution, the protein should be stored at 4°C between 2-7 days and for future use below -20°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA) . Please prevent freeze-thaw cycles.

Protein Length

The recombinant Human/Mouse BMP-2 consists of 114 amino acids and predicts a molecular mass of 13 kDa.

Formulation

Lyophilized from sterile 20mM Tris,50mM NaCl, pH 8.0.

Applications Notes

Human/Mouse

Other Product Names

BMP2; BMP2A; Bone morphogenetic protein 2; BMP-2; Bone morphogenetic protein 2A; BMP-2A

Recommended Usage

Always centrifuge tubes before opening. It is recommended to reconstitute the lyophilized Human/Mouse BMP-2 protein using the buffer we provided not less than 100µg/ml, which can then be further diluted to other aqueous solutions.

Preparation

E. coli

Accession Number URL

https://www.uniprot.org/uniprotkb/P12643

AA Sequence

Amino acid sequence derived from Human/Mouse BMP-2 (Gln283-Arg396) (P21274.3) was expressed

Available Sizes

Frequently Asked Questions

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