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Aglafoline

Aglafoline inhibits PAF-induced platelet aggregation, with an IC50 value of 50 μM.

Product Specifications

CAS Number

143901-35-3

Product Name Alternative

Aglafolin; Rocaglamide U; (-) -Methyl rocaglate

UNSPSC

12352005

Target

Potassium Channel

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel

Applications

COVID-19-immunoregulation

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/Aglafoline.html

Concentration

10mM

Purity

98.46

Solubility

DMSO : 21.43 mg/mL (ultrasonic) |Ethanol : 100 mg/mL (ultrasonic)

Smiles

O=C([C@H]([C@H]1C2=CC=CC=C2)[C@@H](O)[C@]3(O)[C@@]1(C4=CC=C(OC)C=C4)OC5=CC(OC)=CC(OC)=C35)OC

Molecular Formula

C28H28O8

Molecular Weight

492.52

References & Citations

[1]Ko FN, et al. PAF antagonism in vitro and in vivo by aglafoline from Aglaia elliptifolia Merr. Eur J Pharmacol. 1992 Jul 21;218 (1) :129-35.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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