Hypoglaunine D

Hypoglaunine D is an analogue of Triptonine B and acts as an anti-HIV compound. Hypoglaunine D inhibits HIV replication in H9 lymphocytes with an EC50 value of 22 μg/ml[1].

Product Specifications

CAS Number

[220751-00-8]

UNSPSC

12352005

Target

HIV

Type

Natural Products

Related Pathways

Anti-infection

Applications

COVID-19-anti-virus

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/hypoglaunine-d.html

Solubility

10 mM in DMSO

Smiles

O=C(C1=COC=C1)OC[C@]23[C@@]45[C@@H]([C@]([C@H]([C@H]3OC(C)=O)OC(C)=O)([H])[C@@](O4)(COC(C6=CN=CC=C6C(C(C(O[C@]([C@@H]([C@@H]2OC(C)=O)OC(C)=O)([H])[C@@]5(O)C)=O)C)C)=O)C)OC(C)=O

Molecular Formula

C41H47NO19

Molecular Weight

857.81

References & Citations

[1]H Duan, et al. Sesquiterpene alkaloids from Tripterygium hypoglaucum and Tripterygium wilfordii: a new class of potent anti-HIV agents. J Nat Prod. 2000 Mar;63 (3) :357-61.