N- (Azido-PEG3) -N-Biotin-PEG4-methyl ester
N- (Azido-PEG3) -N-Biotin-PEG4-methyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. N- (Azido-PEG3) -N-Biotin-PEG4-methyl ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
Product Specifications
CAS Number
[2100306-76-9]
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
PROTAC Linkers
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/n-azido-peg3-n-biotin-peg4-methyl-ester.html
Purity
95.86
Solubility
10 mM in DMSO
Smiles
O=C(OC)CCOCCOCCOCCOCCN(C(CCCC[C@H]1SC[C@@]([C@@]1([H])N2)([H])NC2=O)=O)CCOCCOCCOCCN=[N+]=[N-]
Molecular Formula
C30H54N6O11S
Molecular Weight
706.85
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
PEG Linkers
Available Sizes
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