CYP51-IN-18
CYP51-IN-18 (compound 2l) is a potent CYP51 inhibitor with an IC50 of 0.219 μg/mL. CYP51-IN-18 shows significant fungicidal activity against B. cinerea with an EC50 of 0.369 μg/mL[1].
Product Specifications
UNSPSC
12352005
Target
Bacterial; Cytochrome P450; Fungal
Type
Reference compound
Related Pathways
Anti-infection; Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/cyp51-in-18.html
Smiles
FC1=CC=C(C2=NC(C3=CC=C(Br)O3)=C(CN(C4CC4)C/C5=C\C6=CC=C(Br)O6)C5=N2)C=C1
Molecular Formula
C25H18Br2FN3O2
Molecular Weight
571.24
References & Citations
[1]Yan Y, et al. Novel Pyrido [4, 3-d] pyrimidine Derivatives as Potential Sterol 14α-Demethylase Inhibitors: Design, Synthesis, Inhibitory Activity, and Molecular Modeling[J]. Journal of Agricultural and Food Chemistry, 2024.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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