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CYP51-IN-18

CYP51-IN-18 (compound 2l) is a potent CYP51 inhibitor with an IC50 of 0.219 μg/mL. CYP51-IN-18 shows significant fungicidal activity against B. cinerea with an EC50 of 0.369 μg/mL[1].

Product Specifications

UNSPSC

12352005

Target

Bacterial; Cytochrome P450; Fungal

Type

Reference compound

Related Pathways

Anti-infection; Metabolic Enzyme/Protease

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/cyp51-in-18.html

Smiles

FC1=CC=C(C2=NC(C3=CC=C(Br)O3)=C(CN(C4CC4)C/C5=C\C6=CC=C(Br)O6)C5=N2)C=C1

Molecular Formula

C25H18Br2FN3O2

Molecular Weight

571.24

References & Citations

[1]Yan Y, et al. Novel Pyrido [4, 3-d] pyrimidine Derivatives as Potential Sterol 14α-Demethylase Inhibitors: Design, Synthesis, Inhibitory Activity, and Molecular Modeling[J]. Journal of Agricultural and Food Chemistry, 2024.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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