Lycoramine

Lycoramine, a dihydro-derivative of galanthamine, is isolated from Lycoris radiate. Lycoramine is a potent acetylcholinesterase (AChE) inhibitor[1][2].

Product Specifications

CAS Number

[21133-52-8]

UNSPSC

12352005

Hazard Statement

H301-H315-H317-H331

Target

Cholinesterase (ChE)

Type

Natural Products

Related Pathways

Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/lycoramine.html

Purity

99.83

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O[C@H]1CC[C@]23C4=C(O[C@]3(C1)[H])C(OC)=CC=C4CN(CC2)C

Molecular Formula

C17H23NO3

Molecular Weight

289.38

Precautions

P261-P261-P264-P264-P270-P271-P272-P280-P280-P302+P352-P302+P352-P304+P340-P330-P362-P363-P405-P405-P501-P501-P501

References & Citations

[1]Yuan Y, et, al. Online acetylcholinesterase inhibition evaluation by high-performance liquid chromatography-mass spectrometry hyphenated with an immobilized enzyme reactor. J Chromatogr A. 2020 Jan 4; 1609:460506.|[2]IRWIN RL, et, al. Cholinesterase inhibition by galanthamine and lycoramine. Biochem Pharmacol. 1960 May; 3:147-8.