DCZ5418
DCZ5418 is an inhibitor of TRIP13. DCZ5418 has anti-multiple myeloma activity in vitro and in vivo[1].
Product Specifications
CAS Number
[2883709-99-5]
UNSPSC
12352005
Target
Apoptosis; NF-κB
Type
Reference compound
Related Pathways
Apoptosis; NF-κB
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/dcz5418.html
Purity
99.02
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(N1C2=CC=C(C=C2)CC3=CC=NC=C3)[C@@]4(C)[C@@]([C@@H]5CC[C@H]4O5)(C)C1=O
Molecular Formula
C22H22N2O3
Molecular Weight
362.42
References & Citations
[1]Sanfeng Dong, et al. Design and synthesis of cantharidin derivative DCZ5418 as a TRIP13 inhibitor with anti-multiple myeloma activity in vitro and in vivo. Bioorg Med Chem Lett. 2023.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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