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ST-IN-1

Product Specifications

UNSPSC Description

ST-IN-1 (compound (R)-1) is a selective ST inhibitor (Ki=70 nM, rat a-2,6-ST; Ki=19 nM, hST6GAL1) with antitumor activity. ST-IN-1 inhibits tumor growth and metastasis by delipidating the surface of tumor cells[1].

Target Antigen

Glycosyltransferase

Type

Reference compound

Related Pathways

Epigenetics

Field of Research

cancer

Assay Protocol

https://www.medchemexpress.com/st-in-1.html

Smiles

O[C@H]1[C@@H](O)[C@H](N2C(NC(C=C2)=O)=O)O[C@@H]1COP(O)(OC(P(O)(O)=O)C3=CC=CC(OC4=CC=CC=C4)=C3)=O

Molecular Weight

586.38

References & Citations

[1]Szabo, et al. "Synthesis of α‐Hydroxy‐1, 2, 3‐Triazole‐linked Sialyltransferase Inhibitors and Evaluation of Selectivity Towards ST3GAL1, ST6GAL1 and ST8SIA2." ChemMedChem 19.16 (2024): e202400088.

Shipping Conditions

Room temperature

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-169084/ST-IN-1-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-169084/

Clinical Information

No Development Reported

Curated Selection

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