ST-IN-1
ST-IN-1 (compound (R) -1) is a selective ST inhibitor (Ki=70 nM, rat a-2,6-ST; Ki=19 nM, hST6GAL1) with antitumor activity. ST-IN-1 inhibits tumor growth and metastasis by delipidating the surface of tumor cells[1].
Product Specifications
UNSPSC
12352005
Target
Glycosyltransferase
Type
Reference compound
Related Pathways
Epigenetics
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/st-in-1.html
Smiles
O[C@H]1[C@@H](O)[C@H](N2C(NC(C=C2)=O)=O)O[C@@H]1COP(O)(OC(P(O)(O)=O)C3=CC=CC(OC4=CC=CC=C4)=C3)=O
Molecular Formula
C22H24N2O13P2
Molecular Weight
586.38
References & Citations
[1]Szabo, et al. "Synthesis of α‐Hydroxy‐1, 2, 3‐Triazole‐linked Sialyltransferase Inhibitors and Evaluation of Selectivity Towards ST3GAL1, ST6GAL1 and ST8SIA2." ChemMedChem 19.16 (2024) : e202400088.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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