TMEM219/IGFBP-3R, Mouse (HEK293, Fc)

The IGFBP-3R protein was identified as an IGFBP3-specific cell death receptor and becomes a potential mediator of caspase-8-dependent apoptosis upon ligand binding. This receptor actively interacts with IGFBP3, forming a key molecular connection that may initiate the apoptotic signaling cascade. TMEM219/IGFBP-3R Protein, Mouse (HEK293, Fc) is the recombinant mouse-derived IGFBP-3R protein, expressed by HEK293 , with C-hFc labeled tag.