Antibacterial agent 205
Product Specifications
UNSPSC Description
Antibacterial agent 205 (Compound 10d) is a indolylacryloyl-derived oxacins, which exhibits broad antibacterial spectrum with MIC of 0.25-0.5 μg/mL. Antibacterial agent 205 reduces the exopolysaccharide, eliminates the biofilm, and thus attenuates the drug resistance. Antibacterial agent 205 exhibits antibacterial activity through destory of membrane integrity, accumulation of reactive oxygen species ROS, and inhibition of DNA replication[1].
Target Antigen
Bacterial
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/antibacterial-agent-205.html
Solubility
10 mM in DMSO
Smiles
O=C(N1CCN(C2=C(F)C=C3C(N(CC)C=C(C(O)=O)C3=O)=C2)CC1)/C(C#N)=C/C4=CN(CC(OCC)=O)C5=C4C=CC=C5
Molecular Weight
599.61
References & Citations
[1]Hu YG, et al., Discovery of indolylacryloyl-derived oxacins as novel potential broad-spectrum antibacterial candidates. Eur J Med Chem. 2024 Apr 15;270:116392.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-162429/Antibacterial-agent-205-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-162429/
Clinical Information
No Development Reported
CAS Number
9007-83-4
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
