Pyroglutamylated RFamide Peptide (Human)

<strong>Pyroglutamylated RFamide Peptide (Human)</strong> <strong>Catalog number:</strong> MDP0781 <strong>CAS Number: </strong>311309-27-0 <strong>Sequence: </strong>Pyr-Asp-Glu-Gly-Ser-Glu-Ala-Thr-Gly-Phe-Leu-Pro-Ala-Ala-Gly-Glu-Lys-Thr-Ser-Gly-Pro-Leu-Gly-Asn-Leu-Ala-Glu-Glu-Leu-Asn-Gly-Tyr-Ser-Arg-Lys-Lys-Gly-Gly-Phe-Ser-Phe-Arg-Phe-NH2 <strong>Amount:</strong> 100 ug <strong>Molecular Weight:</strong> 4503.6 g/mol <strong>Supplied as:</strong> Powder <strong>Applications:</strong> molecular tool for various biochemical applications <strong>Storage:</strong> -20 °C <strong>WARNING:</strong> For in vitro Research Use Only. NOT for use on humans or animals. <strong>Grade:</strong> Biotechnology grade. All products are highly pure. <strong>References:</strong> 1: Patel SK, Singh SK. Pyroglutamylated RFamide peptide 43: A putative modulator of testicular steroidogenesis Andrology. 2020 Nov;8(6):1815-1823. 2: Patel SK, Singh SK. Pyroglutamylated RFamide peptide (QRFP): Role in early testicular development in relation to Sertoli cell maturation in prepubertal mice Neuropeptides. 2022 Feb;91:102215. 3: Patel SR, Murphy KG, Thompson EL, Patterson M, Curtis AE, Ghatei MA, Bloom SR. Pyroglutamylated RFamide peptide 43 stimulates the hypothalamic-pituitary-gonadal axis via gonadotropin-releasing hormone in rats Endocrinology. 2008 Sep;149(9):4747-54. 4: Osugi T, Son YL, Ubuka T, Satake H, Tsutsui K. RFamide peptides in agnathans and basal chordates Gen Comp Endocrinol. 2016 Feb 1;227:94-100. 5: Ishigame N, Kageyama K, Takayasu S, Furumai K, Nakada Y, Daimon M. Regulation of the expression of corticotropin-releasing factor gene by pyroglutamylated RFamide peptide in rat hypothalamic 4B cells Endocr J. 2016 Oct 29;63(10):919-927. 6: Tsutsui K, Osugi T, Son YL, Ubuka T. Review: Structure, function and evolution of GnIH Gen Comp Endocrinol. 2018 Aug 1;264:48-57. 7: Elphick MR, Mirabeau O. The Evolution and Variety of RFamide-Type Neuropeptides: Insights from Deuterostomian Invertebrates Front Endocrinol (Lausanne). 2014 Jun 19;5:93. 8: Fukusumi S, Fujii R, Hinuma S. Recent advances in mammalian RFamide peptides: the discovery and functional analyses of PrRP, RFRPs and QRFP Peptides. 2006 May;27(5):1073-86. 9: Machado N, Raffin F, Kaur S, Banks A, Lynch N, Fanari O, Plascencia O, Aten S, Lima J, Bandaru S, Palmiter R, Arrigoni E, Saper C. Prolonged activation of EP3 receptor-expressing preoptic neurons underlies torpor responses Res Sq. 2023 May 2:rs.3.rs-2861253. <a href="https://pubmed.ncbi.nlm.nih.gov/33655503">10: Wang W, Tian Y, Shi X, Ma Q, Xu Y, Yang G, Yi W, Shi Y, Zhou N. N-glycosylation of the human neuropeptide QRFP receptor (QRFPR) is essential for ligand binding and receptor activation J Neurochem. 2021 Jul;158(2):138-152. </a> <br><strong>Products Related to Pyroglutamylated RFamide Peptide (Human) can be found at</strong> <a href="https://moleculardepot.com/product-category/Peptides/"> Peptides</a>