Alisol B

Alisol B is a potential compound for researching orthopedic diseases, acting by influencing the differentiation of osteoclasts and their function.

Product Specifications

CAS Number

[18649-93-9]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Others

Type

Natural Products

Related Pathways

Others

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/Alisol-B.html

Concentration

10mM

Purity

99.57

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

C[C@]([C@@]1(C2=C([C@H](C)C[C@@H]([C@]3([H])C(C)(C)O3)O)CC1)C)(CC[C@@]4([H])C5(C)C)[C@]([C@H](C2)O)([H])[C@]4(CCC5=O)C

Molecular Formula

C30H48O4

Molecular Weight

472.70

Precautions

H302, H315, H319, H335

References & Citations

[1]Zhang RF, et al.[Alisol B inhibited complement 3a-induced human renal tubular epithelial to mesenchymal transition]. Zhongguo Zhong Xi Yi Jie He Za Zhi. 2012 Oct;32 (10) :1407-12.|[2]Lee JW, et al. Alisol-B, a novel phyto-steroid, suppresses the RANKL-induced osteoclast formation and prevents bone loss in mice. Biochem Pharmacol. 2010 Aug 1;80 (3) :352-61.|[3]Law BY, et al. Alisol B, a novel inhibitor of the sarcoplasmic/endoplasmic reticulum Ca (2+) ATPase pump, induces autophagy, endoplasmic reticulum stress, and apoptosis. Mol Cancer Ther. 2010 Mar;9 (3) :718-30.