(4-NH2) -Exatecan
(4-NH2) -Exatecan (compound A), a topoisomerase inhibitor, is a derivative of Exatecan. (4-NH2) -Exatecan can be used in the synthesis of antibody-drug conjugates (ADCs) [1].
Product Specifications
CAS Number
[2495742-21-5]
Product Name Alternative
AZ14170132
UNSPSC
12352005
Hazard Statement
H301
Target
ADC Payload; Topoisomerase
Type
Reference compound
Related Pathways
Antibody-drug Conjugate/ADC Related; Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/4-nh2-exatecan.html
Purity
99.93
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C1N2C(C(C(C2)=C3C4=C5CCC3)=NC4=CC=C5N)=CC6=C1COC([C@]6(O)CC)=O
Molecular Formula
C23H21N3O4
Molecular Weight
403.43
Precautions
H301
References & Citations
[1]Howard PW, et, al. Compounds and conjugates thereof. US20200306243A1.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Camptothecins
Available Sizes
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
Recombinant Human Pregnancy-Specific beta-1-Glycoprotein 9/PSBG9 (C-6His)
