MCL0020
MCL0020 is a potent and selective melanocortin MC4 receptor antagonist, with an IC50 of 11.63 nM. MCL0020 dose-dependently and significantly attenuates restraint stress-induced anorexia without affecting food intake[1].
Product Specifications
CAS Number
[475498-26-1]
UNSPSC
12352209
Hazard Statement
H302, H315, H319
Target
Melanocortin Receptor
Type
Peptides
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/mcl0020.html
Purity
99.93
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
NC([C@H](CC1=CC2=C(C=CC=C2)C=C1)NC([C@H](CCCNC(N)=N)NC([C@H](NC(C)=O)CC3=CC4=C(C=CC=C4)C=C3)=O)=O)=O
Molecular Formula
C34H39N7O4
Molecular Weight
609.72
Precautions
H302, H315, H319
References & Citations
[1]Chaki S, et al. Involvement of the melanocortin MC4 receptor in stress-related behavior in rodents. Eur J Pharmacol. 2003;474 (1) :95-101.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Scientific Category
Peptides
Clinical Information
No Development Reported
Isoform
MC4R
Available Sizes
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
