PDGF-BB Monoclonal Antibody

<strong>PDGF-BB Monoclonal Antibody</strong>_x000D_ <strong>Catalog number:</strong> B2015293_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 10 µg_x000D_ <strong>Molecular Weight or Concentration:</strong> N/A_x000D_ <strong>Supplied as:</strong> Solution_x000D_ <strong>Applications:</strong> a molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> -20¬∞C_x000D_ <strong>Keywords:</strong> PDGF-BB Monoclonal antibody_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MŒ©-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Kuai J, Mosyak L, Brooks J, Cain M, Carven GJ, Ogawa S, Ishino T, Tam M, Lavallie ER, Yang Z, Ponsel D, Rauchenberger R, Arch R, Pullen N. Characterization of binding mode of action of a blocking anti-platelet-derived growth factor (PDGF)-B monoclonal antibody, MOR8457, reveals conformational flexibility and avidity needed for PDGF-BB to bind PDGF receptor-Œ≤ Biochemistry. 2015 Mar 17;54(10):1918-29._x000D_ 2: Ogawa S, Ochi T, Shimada H, Inagaki K, Fujita I, Nii A, Moffat MA, Katragadda M, Violand BN, Arch RH, Masferrer JL. Anti-PDGF-B monoclonal antibody reduces liver fibrosis development Hepatol Res. 2010 Nov;40(11):1128-41._x000D_ 3: Cheng N, Liu Y, Mukama O, Han X, Huang H, Li S, Zhou P, Lu X, Li Z. A signal-enhanced and sensitive lateral flow aptasensor for the rapid detection of PDGF-BB RSC Adv. 2020 May 18;10(32):18601-18607._x000D_ 4: Hosaka K, Yang Y, Seki T, Nakamura M, Andersson P, Rouhi P, Yang X, Jensen L, Lim S, Feng N, Xue Y, Li X, Larsson O, Ohhashi T, Cao Y. Tumour PDGF-BB expression levels determine dual effects of anti-PDGF drugs on vascular remodelling and metastasis Nat Commun. 2013;4:2129._x000D_ 5: Pierce GF, Tarpley JE, Tseng J, Bready J, Chang D, Kenney WC, Rudolph R, Robson MC, Vande Berg J, Reid P, et al. Detection of platelet-derived growth factor (PDGF)-AA in actively healing human wounds treated with recombinant PDGF-BB and absence of PDGF in chronic nonhealing wounds J Clin Invest. 1995 Sep;96(3):1336-50._x000D_ 6: Battegay EJ, Rupp J, Iruela-Arispe L, Sage EH, Pech M. PDGF-BB modulates endothelial proliferation and angiogenesis in vitro via PDGF beta-receptors J Cell Biol. 1994 May;125(4):917-28._x000D_ 7: Vassbotn FS, Langeland N, Hagen I, Holmsen H. A monoclonal antibody against PDGF B-chain inhibits PDGF-induced DNA synthesis in C3H fibroblasts and prevents binding of PDGF to its receptor Biochim Biophys Acta. 1990 Sep 1;1054(2):246-9._x000D_ 8: Hart CE, Bailey M, Curtis DA, Osborn S, Raines E, Ross R, Forstrom JW. Purification of PDGF-AB and PDGF-BB from human platelet extracts and identification of all three PDGF dimers in human platelets Biochemistry. 1990 Jan 9;29(1):166-72._x000D_ 9: Inanc M, Sirakaya HA, Karaman H, Bozkurt O. The prognostic importance of VEGF-A, PDGF-BB and c-MET in patients with metastatic colorectal cancer J Oncol Pharm Pract. 2020 Dec;26(8):1878-1885._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/16557224">10: van Roeyen CR, Ostendorf T, Denecke B, Bokemeyer D, Behrmann I, Strutz F, Lichenstein HS, LaRochelle WJ, Pena CE, Chaudhuri A, Floege J. Biological responses to PDGF-BB versus PDGF-DD in human mesangial cells Kidney Int. 2006 Apr;69(8):1393-402. </a>_x000D_ _x000D_ <strong>Products Related to PDGF-BB Monoclonal Antibody can be found at</strong> <a href="https://moleculardepot.com/product-category/Antibodies/"> Antibodies</a>