UNC8732 (TFA)

UNC8732 (TFA) is a NSD2 inhibitor and degrader[1].

Product Specifications

CAS Number

[2929304-06-1]

UNSPSC

12352005

Target

Histone Methyltransferase; Molecular Glues

Type

Reference compound

Related Pathways

Epigenetics; PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/unc8732-tfa.html

Purity

99.07

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C(C(F)(F)F)O.O=C(C1=CC=C(CN(C2CC2)C(C3=CC=C4NC(COC4=C3)=O)=O)C=C1)NC5=CC=C6C(CCN(C6)C(CCCCCN)=O)=C5

Molecular Formula

C37H40F3N5O7

Molecular Weight

723.74

References & Citations

[1]David Y Nie, et al. Recruitment of FBXO22 for targeted degradation of NSD2. Nat Chem Biol. 2024 Dec;20 (12) :1597-1607.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C, 3 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

E9085 100 µg

Ezh1 (Enhancer of Zeste Homolog 1, ENX-2, KIAA0388, Polycomb group (PcG) Protein)

Ask

View Details

P505844 100 µg

MARCKS Protein (N-His, Human)

Ask

View Details

NBP2-71744PCP 0.1 mL

Mouse Monoclonal LEMD3 Antibody (OTI6C10) [PerCP]

Ask

View Details

TA502748 100 µL

LNK (SH2B3) Mouse Monoclonal Antibody [Clone ID: OTI2B11]

Ask

View Details

FY-AB38844-01 1 mL

Anti-Endothelin 2 (EDN2) Polyclonal antibody

Ask

View Details

FY-AB38844-02 100 µL

Anti-Endothelin 2 (EDN2) Polyclonal antibody

Ask

View Details