UNC8732 (TFA)
UNC8732 (TFA) is a NSD2 inhibitor and degrader[1].
Product Specifications
CAS Number
[2929304-06-1]
UNSPSC
12352005
Target
Histone Methyltransferase; Molecular Glues
Type
Reference compound
Related Pathways
Epigenetics; PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/unc8732-tfa.html
Purity
99.07
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(C(F)(F)F)O.O=C(C1=CC=C(CN(C2CC2)C(C3=CC=C4NC(COC4=C3)=O)=O)C=C1)NC5=CC=C6C(CCN(C6)C(CCCCCN)=O)=C5
Molecular Formula
C37H40F3N5O7
Molecular Weight
723.74
References & Citations
[1]David Y Nie, et al. Recruitment of FBXO22 for targeted degradation of NSD2. Nat Chem Biol. 2024 Dec;20 (12) :1597-1607.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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