Cholestenone-13C2
Product Specifications
Product Name Alternative
PF-2545920 (succinate)
UNSPSC Description
Cholestenone-13C2 is the 13C labeled Cholestenone. Cholestenone (4-Cholesten-3-one), the intermediate oxidation product of cholesterol, is metabolized primarily in the liver. Cholestenone is highly mobile in membranes and influences cholesterol flip-flop and efflux. Cholestenone may cause long-term functional defects in cells[1][2][3].
Target Antigen
Endogenous Metabolite; Isotope-Labeled Compounds
Type
Isotope-Labeled Compounds
Related Pathways
Metabolic Enzyme/Protease;Others
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/cholestenone-13c2.html
Solubility
10 mM in DMSO
Smiles
CC(C)CCC[C@@H](C)[C@H]1CC[C@@]2([H])[C@]3([H])CCC4=[13CH][13C](CC[C@]4(C)[C@@]3([H])CC[C@]12C)=O
Molecular Weight
386.62
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.|[2]Neuvonen M, et, al. Enzymatic oxidation of cholesterol: properties and functional effects of cholestenone in cell membranes. PLoS One. 2014 Aug 26;9(8):e103743.|[3]Rosenheim O, et al. The mechanism of coprosterol formation in vivo: 1. Cholestenone as an intermediate. Biochem J. 1943 Oct;37(4):513-4.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-113365S2/Cholestenone-13C2-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-113365S2/
Clinical Information
No Development Reported
CAS Number
82938-09-8
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
abx338331-01 20 µg
Xin actin-binding repeat-containing protein 2 (XIRP2) Antibody (Biotin)
Ask
View Details abx338331-02 50 µg
Xin actin-binding repeat-containing protein 2 (XIRP2) Antibody (Biotin)
Ask
View Details 
abx338331-03 100 µg
Xin actin-binding repeat-containing protein 2 (XIRP2) Antibody (Biotin)
Ask
View Details abx338331-04 200 µg
Xin actin-binding repeat-containing protein 2 (XIRP2) Antibody (Biotin)
Ask
View Details abx338331-05 1 mg
Xin actin-binding repeat-containing protein 2 (XIRP2) Antibody (Biotin)
Ask
View Details