Cyclosporin C

Cyclosporin C is a fungal metabolite that has been found in T. inflatum and has diverse biological activities, including antifungal, antiviral, and immunosuppressant properties. Cyclosporin C shows no activity against bacteria or yeasts[1][2][3].

Product Specifications

CAS Number

[59787-61-0]

UNSPSC

12352005

Hazard Statement

H302, H350, H362

Target

Bacterial; Fungal

Type

Natural Products

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/cyclosporin-c.html

Purity

99.97

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O[C@@H]([C@](C(N[C@@](C(N(CC(N([C@H](C(N[C@H](C(N([C@H]1CC(C)C)C)=O)C(C)C)=O)CC(C)C)C)=O)C)=O)([H])[C@H](O)C)=O)([H])N(C([C@@H](N(C([C@@H](N(C([C@@H](N(C([C@H](NC([C@@H](NC1=O)C)=O)C)=O)C)CC(C)C)=O)C)CC(C)C)=O)C)C(C)C)=O)C)[C@H](C)C/C=C/C

Molecular Formula

C62H111N11O13

Molecular Weight

1218.61

Precautions

H302, H350, H362

References & Citations

[1]1. Moussaïf M, et al. Cyclosporin C is the main antifungal compound produced by Acremonium luzulae. Appl Environ Microbiol. 1997 May;63 (5) :1739-43.|[2]2. Damaso CR, et al. Inhibition of vaccinia virus replication by cyclosporin A analogues correlates with their affinity for cellular cyclophilins. J Gen Virol. 1998 Feb;79 (Pt 2) :339-46.|[3]3. Sadeg N, et al. In vitro and in vivo comparative studies on immunosuppressive properties of cyclosporines A, C, D and metabolites M1, M17 and M21. Immunopharmacol Immunotoxicol.