Gardiquimod (diTFA)
Gardiquimod diTFA is an imidazoline TLR7/8 agonist. Gardiquimod diTFA inhibits HIV-1 infection of macrophages and activated peripheral blood mononuclear cells (PBMCs) . Gardiquimod diTFA specifically activates TLR7 at concentrations below 10 μM.
Product Specifications
CAS Number
1159840-61-5
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Toll-like Receptor (TLR)
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/Gardiquimod_trifluoroacetate.html
Purity
99.0
Solubility
DMSO : 50 mg/mL (ultrasonic) |H2O : 25 mg/mL (ultrasonic)
Smiles
OC(C)(C)CN1C(CNCC)=NC2=C1C3=CC=CC=C3N=C2N.FC(C(O)=O)(F)F.FC(C(O)=O)(F)F
Molecular Formula
C21H25F6N5O5
Molecular Weight
541.44
Precautions
H302, H315, H319, H335
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
HIV-1; TLR7; TLR8
Available Sizes
Frequently Asked Questions
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