Human CA12 Protein

<strong>Human CA12 Protein</strong>_x000D_ <strong>Catalog number:</strong> B2011665_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 50 µg_x000D_ <strong>Molecular Weight or Concentration:</strong> 500 µg/mL_x000D_ <strong>Supplied as:</strong> Solution_x000D_ <strong>Applications:</strong> molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> -20 °C_x000D_ <strong>Keywords:</strong> Human CA12 protein, Recombinant CA12 protein, Carbonic anhydrase 12 isoform 1 protein, CAXII protein, HsT18816 protein_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Chen S, Fang XQ, Wang Q, Wang SW, Hu ZJ, Zhou ZJ, Xu WB, Wang JY, Qin A, Fan SW. PHD/HIF-1 upregulates CA12 to protect against degenerative disc disease: a human sample, in vitro and ex vivo study Lab Invest. 2016 May;96(5):561-9._x000D_ 2: Santangelo A, Rossato M, Lombardi G, Benfatto S, Lavezzari D, De Salvo GL, Indraccolo S, Dechecchi MC, Prandini P, Gambari R, Scapoli C, Di Gennaro G, Caccese M, Eoli M, Rudà R, Brandes AA, Ibrahim T, Rizzato S, Lolli I, Lippi G, Delledonne M, Zagonel V, Cabrini G. A molecular signature associated with prolonged survival in glioblastoma patients treated with regorafenib Neuro Oncol. 2021 Feb 25;23(2):264-276._x000D_ 3: Liao SY, Ivanov S, Ivanova A, Ghosh S, Cote MA, Keefe K, Coca-Prados M, Stanbridge EJ, Lerman MI. Expression of cell surface transmembrane carbonic anhydrase genes CA9 and CA12 in the human eye: overexpression of CA12 (CAXII) in glaucoma J Med Genet. 2003 Apr;40(4):257-61._x000D_ 4: Du Y, Xin Z, Liu T, Xu P, Mao F, Yao J. Overexpressed CA12 has prognostic value in pancreatic cancer and promotes tumor cell apoptosis via NF-κB signaling J Cancer Res Clin Oncol. 2021 May;147(5):1557-1564._x000D_ 5: Huang T, Tang L, Wang H, Lin L, Fu J. Carbonic anhydrase 12 gene silencing reverses the sensitivity of paclitaxel in drug-resistant breast cancer cells Bioengineered. 2021 Dec;12(2):9806-9818._x000D_ 6: Colares HC, Guimarães GM, Couto CAP, Gil PO, Santos SLEN, Silva TNL, de Carvalho ILQ, da Fonseca FG, Gagnon M, Roy D, de Magalhães JT, Gonçalves DB, Granjeiro PA. Optimization of bioprocess of Schleiferilactobacillus harbinensis Ca12 and its viability in frozen Brazilian berries (Açai, Euterpe oleracea Mart.) Braz J Microbiol. 2021 Dec;52(4):2271-2285._x000D_ 7: Shen M, Yang L, Lei T, Zhang P, Xiao L, Cao S, Chen F, Li L, Ye F, Bu H. Correlation between CA12 and TFF3 and their prediction value of neoadjuvant chemotherapy response in breast cancer J Clin Pharm Ther. 2022 May;47(5):609-618._x000D_ 8: Franke CM, Gu VW, Grimm BG, Cassady VC, White JR, Weigel RJ, Kulak MV. TFAP2C regulates carbonic anhydrase XII in human breast cancer Oncogene. 2020 Feb;39(6):1290-1301._x000D_ 9: Uda NR, Stenner F, Seibert V, Herzig P, Markuly N, VAN Dijk M, Zippelius A, Renner C. Humanized Monoclonal Antibody Blocking Carbonic Anhydrase 12 Enzymatic Activity Leads to Reduced Tumor Growth In Vitro Anticancer Res. 2019 Aug;39(8):4117-4128._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/33528822">10: El Moussawi Z, Boueiri M, Al-Haddad C. Gene therapy in color vision deficiency: a review Int Ophthalmol. 2021 May;41(5):1917-1927. </a>_x000D_ _x000D_ <strong>Products Related to Human CA12 Protein can be found at</strong> <a href="https://moleculardepot.com/product-category/Proteins/"> Proteins</a>