STAT3-IN-3
Product Specifications
UNSPSC Description
STAT3-IN-3 is a potent and selective inhibitor of signal transducer and activator of transcription 3 (STAT3), with anti-proliferative activity. STAT3-IN-3 induces apoptosis in breast cancer cells. STAT3-IN-3 acts as a promising mitochondria-targeting STAT3 inhibitor for cancer research[1].
Target Antigen
Apoptosis; STAT
Type
Reference compound
Related Pathways
Apoptosis;JAK/STAT Signaling;Stem Cell/Wnt
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/stat3-in-3.html
Purity
98.40
Solubility
DMSO : 5 mg/mL (ultrasonic)
Smiles
BrC1=C2C(S(C(C(N3CCN(C(C4=CC5=CC=C(N(CC)CC)C=C5OC4=O)=O)CC3)=O)=C2)(=O)=O)=CC=C1
Molecular Weight
600.48
References & Citations
[1]Cai G, et al. Discovery of fluorescent coumarin-benzo[b]thiophene 1, 1-dioxide conjugates as mitochondria-targeting antitumor STAT3 inhibitors. Eur J Med Chem. 2019 Jul 15;174:236-251.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-128588/STAT3-IN-3-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-128588/STAT3-IN-3-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
2361304-26-7
Available Sizes
Curated Selection
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