What is the catalog number for Olesoxime?

The catalog number for Olesoxime is HY-14796.

What sizes are available for Olesoxime?

Olesoxime is available in the following size(s): 5 mg, 10 mM - 1 mL, 10 mg, 50 mg.

How many pack sizes does Olesoxime come in?

Olesoxime is available in 4 different pack sizes.

Is Olesoxime in stock?

Olesoxime is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Olesoxime?

Olesoxime is manufactured by QuantiMol.

What is the estimated delivery time for Olesoxime?

Estimated delivery time for Olesoxime is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Olesoxime?

The safety data sheet for Olesoxime is available here: http://file.medchemexpress.com/batch_PDF/HY-14796/Olesoxime-SDS-MedChemExpress.pdf.

Olesoxime

Olesoxime (TRO 19622) is a mitochondrial-targeted neuroprotective compound with mean EC50 value for increasing cell survival is 3.2±0.2 μM.

Product Specifications

CAS Number

22033-87-0

Product Name Alternative

TRO 19622; NSC 21311

UNSPSC

12352211

Hazard Statement

H302, H315, H319, H335

Target

Mitochondrial Metabolism

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/TRO-19622.html

Purity

99.09

Solubility

DMSO : 50 mg/mL (ultrasonic)

Smiles

C[C@@]12C(CC[C@]3([H])[C@]2([H])CC[C@@]4(C)[C@@]3([H])CC[C@@]4([C@]([H])(C)CCCC(C)C)[H])=CC(CC1)=NO

Molecular Formula

C27H45NO

Molecular Weight

399.65

Precautions

H302, H315, H319, H335

References & Citations

[1]Martin LJ, et al. Olesoxime, a cholesterol-like neuroprotectant for the potential treatment of amyotrophic lateral sclerosis. IDrugs. 2010 Aug;13 (8) :568-80.|[2]Bordet T, et al. Olesoxime (TRO19622) : A Novel Mitochondrial-Targeted Neuroprotective Compound. Pharmaceuticals (Basel) . 2010 Jan 28;3 (2) :345-368|[3]Bordet T, et al. Identification and characterization of cholest-4-en-3-one, oxime (TRO19622), a novel drug candidate for amyotrophic lateral sclerosis. J Pharmacol Exp Ther. 2007 Aug;322 (2) :709-20.|[4]Xiao WH, et al. Olesoxime (cholest-4-en-3-one, oxime) : analgesic and neuroprotective effects in a rat model of painful peripheral neuropathy produced by the chemotherapeutic agent, paclitaxel. Pain. 2009 Dec 15;147 (1-3) :202-9