Pomalidomide-C2-acid
Pomalidomide-C2-acid is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and a linker used in PROTAC technology[1].
Product Specifications
CAS Number
2225940-46-3
UNSPSC
12352005
Hazard Statement
H361
Target
E3 Ligase Ligand-Linker Conjugates
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/pomalidomide-c2-acid.html
Purity
99.78
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
O=C(CCNC1=CC=CC(C(N2C3C(NC(CC3)=O)=O)=O)=C1C2=O)O
Molecular Formula
C16H15N3O6
Molecular Weight
345.31
Precautions
H361
References & Citations
[1]Md Kabir, et al. Discovery and Characterization of a Novel Cereblon-Recruiting PRC1 Bridged PROTAC Degrader. J Med Chem. 2024 Apr 25;67 (8) :6880-6892.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
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Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Cereblon
Available Sizes
Frequently Asked Questions
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