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Pomalidomide-C2-acid

Pomalidomide-C2-acid is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and a linker used in PROTAC technology[1].

Product Specifications

CAS Number

2225940-46-3

UNSPSC

12352005

Hazard Statement

H361

Target

E3 Ligase Ligand-Linker Conjugates

Type

Reference compound

Related Pathways

PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/pomalidomide-c2-acid.html

Purity

99.78

Solubility

DMSO : 50 mg/mL (ultrasonic)

Smiles

O=C(CCNC1=CC=CC(C(N2C3C(NC(CC3)=O)=O)=O)=C1C2=O)O

Molecular Formula

C16H15N3O6

Molecular Weight

345.31

Precautions

H361

References & Citations

[1]Md Kabir, et al. Discovery and Characterization of a Novel Cereblon-Recruiting PRC1 Bridged PROTAC Degrader. J Med Chem. 2024 Apr 25;67 (8) :6880-6892.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Badge

Hot

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

Cereblon

Available Sizes

Frequently Asked Questions

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