CDK7tide Derived Peptide - (5-FAM) labeled

<strong>CDK7tide Derived Peptide - (5-FAM) labeled</strong>_x000D_ <strong>Catalog number:</strong> B2019487_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 1 mg_x000D_ <strong>Molecular Weight or Concentration:</strong> 2072.3_x000D_ <strong>Supplied as:</strong> Powder_x000D_ <strong>Applications:</strong> a molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> -20°C_x000D_ <strong>Keywords:</strong> 5-FAM-FLAKSFGSPNRAYKK-OH_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Heitz F, Morris MC, Fesquet D, Cavadore JC, Dorée M, Divita G. Interactions of cyclins with cyclin-dependent kinases: a common interactive mechanism Biochemistry. 1997 Apr 22;36(16):4995-5003._x000D_ 2: Dietrich C, Wallenfang K, Oesch F, Wieser R. Translocation of cdk2 to the nucleus during G1-phase in PDGF-stimulated human fibroblasts Exp Cell Res. 1997 Apr 10;232(1):72-8._x000D_ 3: Gaur T, Poddutoori R, Khare L, Bagal B, Rashmi S, Patkar N, Tembhare P, Pg S, Shetty D, Dutt A, Zhang Q, Konopleva M, Platzbeckar U, Gupta S, Samajdar S, Ramchandra M, Khattry N, Hasan SK. Novel covalent CDK7 inhibitor potently induces apoptosis in acute myeloid leukemia and synergizes with Venetoclax J Exp Clin Cancer Res. 2023 Jul 29;42(1):186._x000D_ 4: Korsisaari N, Mäkelä TP. Interactions of Cdk7 and Kin28 with Hint/PKCI-1 and Hnt1 histidine triad proteins J Biol Chem. 2000 Nov 10;275(45):34837-40._x000D_ 5: Lv X, Wang J, Dong Z, Lv F, Qin Y. DNA-Bound peptides control the mRNA transcription through CDK7 Peptides. 2009 Apr;30(4):681-8._x000D_ 6: Heitz F, Morris MC, Fesquet D, Cavadore JC, Dorée M, Divita G. Interactions of cyclins with cyclin-dependent kinases: a common interactive mechanism Biochemistry. 1997 Apr 22;36(16):4995-5003._x000D_ 7: Faust M, Kartarius S, Schwindling SL, Montenarh M. Cyclin H is a new binding partner for protein kinase CK2 Biochem Biophys Res Commun. 2002 Aug 9;296(1):13-9._x000D_ 8: Krempler A, Kartarius S, Günther J, Montenarh M. Cyclin H is targeted to the nucleus by C-terminal nuclear localization sequences Cell Mol Life Sci. 2005 Jun;62(12):1379-87._x000D_ 9: Bockstaele L, Bisteau X, Paternot S, Roger PP. Differential regulation of cyclin-dependent kinase 4 (CDK4) and CDK6, evidence that CDK4 might not be activated by CDK7, and design of a CDK6 activating mutation Mol Cell Biol. 2009 Aug;29(15):4188-200._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/11003668">10: Nishiwaki E, Turner SL, Harju S, Miyazaki S, Kashiwagi M, Koh J, Serizawa H. Regulation of CDK7-carboxyl-terminal domain kinase activity by the tumor suppressor p16(INK4A) contributes to cell cycle regulation Mol Cell Biol. 2000 Oct;20(20):7726-34. </a>_x000D_ _x000D_ <strong>Products Related to CDK7tide Derived Peptide - (5-FAM) labeled can be found at</strong> <a href="https://moleculardepot.com/product-category/Peptides/"> Peptides</a>