Kaempferol 3-O-β-D-galactopyranoside

Kaempferol 3-O-β-D-galactopyranoside (Trifolin) is an orally active flavonoid derivative that can be found in the aerial parts of Consolida oliverana. Kaempferol 3-O-β-D-galactopyranoside exhibits antitumor and cardioprotective effects[1][2][3].

Product Specifications

CAS Number

[23627-87-4]

Product Name Alternative

Trifolin

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Apoptosis

Type

Natural Products

Related Pathways

Apoptosis

Applications

Cancer-programmed cell death

Field of Research

Cancer; Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/kaempferol-3-o-β-d-galactopyranoside.html

Purity

99.58

Solubility

DMSO : 25 mg/mL (ultrasonic)

Smiles

O=C1C2=C(O)C=C(O)C=C2OC(C3=CC=C(O)C=C3)=C1O[C@@H]4O[C@@H]([C@H](O)[C@H](O)[C@H]4O)CO

Molecular Formula

C21H20O11

Molecular Weight

448.38

Precautions

H302, H315, H319, H335

References & Citations

[1]da Silva I, et al. Structure determination of monohydrated trifolin (kaempferol 3-O-β-D-galactopyranoside) from laboratory powder diffraction data. J Pharm Sci. 2011;100 (4) :1588-1593.|[2]Kim MJ, et al. Trifolin induces apoptosis via extrinsic and intrinsic pathways in the NCI-H460 human non-small cell lung-cancer cell line. Phytomedicine. 2016 Sep 15;23 (10) :998-1004.|[3]Zhang F, et al. Trifolin Attenuates Hypertension-Mediated Cardiac Injury by Inhibiting Cardiomyocyte Apoptosis: Mechanistic Insights and Therapeutic Potential. Eur J Pharmacol. 2024 Nov 9:177125.