Ganoderenic acid B

Ganoderenic acid B is a lanostane-type triterpene isolated from Ganoderma lucidum. Ganoderenic acid B exhibits potent reversal effect on ABCB1-mediated multidrug resistance of HepG2/ADM cells to Doxorubicin[1].

Product Specifications

CAS Number

[100665-41-6]

UNSPSC

12352211

Target

P-glycoprotein

Type

Natural Products

Related Pathways

Membrane Transporter/Ion Channel

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/ganoderenic-acid-b.html

Purity

99.95

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

CC1(C)[C@@H](O)CC[C@]2(C)C3=C([C@@]4(C(C[C@H]([C@]4(CC3=O)C)/C(C)=C/C(CC(C)C(O)=O)=O)=O)C)[C@@H](O)CC12

Molecular Formula

C30H42O7

Molecular Weight

514.65

References & Citations

[1]Liu DL, et al. Ganoderma lucidum derived ganoderenic acid B reverses ABCB1-mediated multidrug resistance in HepG2/ADM cells. Int J Oncol. 2015 May;46 (5) :2029-38.