EGFR-IN-130
EGFR-IN-130 (compound 14b) is an EGFR inhibitor and apoptosis inducer. EGFR-IN-130 triggers death of HeLa cancer cells via apoptosis induction.[1].
Product Specifications
UNSPSC
12352005
Target
EGFR
Type
Reference compound
Related Pathways
JAK/STAT Signaling; Protein Tyrosine Kinase/RTK
Applications
COVID-19-immunoregulation
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/egfr-in-130.html
Smiles
OC1=C(CN(C2=CC(C(OC)=O)=C(O)C=C2)C3=NC(/C(S3)=C/C4=CC=C(N(C)C)C=C4)=O)C=C(O)C=C1
Molecular Formula
C27H25N3O6S
Molecular Weight
519.57
References & Citations
[1]Othman SA, et al. Combining lavendustin C and 5-arylidenethiazolin-4-one-based pharmacophores toward multitarget anticancer hybrids. Bioorg Chem. 2024 Dec;153:107884.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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