EGFR-IN-130

EGFR-IN-130 (compound 14b) is an EGFR inhibitor and apoptosis inducer. EGFR-IN-130 triggers death of HeLa cancer cells via apoptosis induction.[1].

Product Specifications

UNSPSC

12352005

Target

EGFR

Type

Reference compound

Related Pathways

JAK/STAT Signaling; Protein Tyrosine Kinase/RTK

Applications

COVID-19-immunoregulation

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/egfr-in-130.html

Smiles

OC1=C(CN(C2=CC(C(OC)=O)=C(O)C=C2)C3=NC(/C(S3)=C/C4=CC=C(N(C)C)C=C4)=O)C=C(O)C=C1

Molecular Formula

C27H25N3O6S

Molecular Weight

519.57

References & Citations

[1]Othman SA, et al. Combining lavendustin C and 5-arylidenethiazolin-4-one-based pharmacophores toward multitarget anticancer hybrids. Bioorg Chem. 2024 Dec;153:107884.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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