TSPO ligand-2
TSPO ligand-2 is a ligand of AUTAC1. AUTAC1 contains an p-fluorobenzylguanine (FBnG) and a Fumagillol moiety, which can silence endogenous MetAP2 in HeLa cells[1].
Product Specifications
CAS Number
1160640-95-8
UNSPSC
12352005
Target
TSPO
Type
Reference compound
Related Pathways
Neuronal Signaling
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/tspo-ligand-2.html
Purity
99.63
Solubility
DMSO : 50 mg/mL (ultrasonic; warming; heat to 70°C)
Smiles
O=C(O[C@H]1[C@@H](OC)[C@@]([C@]2(C)[C@@H](C/C=C(C)\C)O2)([H])[C@]3(OC3)CC1)OC4=CC=C([N+]([O-])=O)C=C4
Molecular Formula
C23H29NO8
Molecular Weight
447.48
References & Citations
[1]Takahashi D, et al. AUTACs: Cargo-Specific Degraders Using Selective Autophagy. Mol Cell. 2019 Dec 5;76 (5) :797-810.e10.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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