Terbutaline

Terbutaline is an orally active β2-adrenergic receptor agonist and an active metabolite of bambuterol[1]. Terbutaline can be used in asthma symptom research[2].

Product Specifications

CAS Number

[23031-25-6]

UNSPSC

12352005

Hazard Statement

H302, H312, H332

Target

Adrenergic Receptor; Antibiotic; Drug Metabolite

Type

Reference compound

Related Pathways

Anti-infection; GPCR/G Protein; Metabolic Enzyme/Protease; Neuronal Signaling

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Endocrinology

Assay Protocol

https://www.medchemexpress.com/terbutaline.html

Purity

99.77

Solubility

DMSO : 233.33 mg/mL (ultrasonic)

Smiles

OC1=CC(C(O)CNC(C)(C)C)=CC(O)=C1

Molecular Formula

C12H19NO3

Molecular Weight

225.29

Precautions

H302, H312, H332

References & Citations

[1]Mohamed Ismail NA, et al. Nifedipine versus terbutaline for tocolysis in external cephalic version. Int J Gynaecol Obstet. 2008 Sep;102 (3) :263-6.|[2]Joana A Loureiro, et al. The interaction of a β2 adrenoceptor agonist drug with biomimetic cell membrane models: The case of terbutaline sulphate. Life Sci. 2021 Nov 15;285:119992.|[3]Tiina Keränen, et al. Anti-Inflammatory Effects of β2-Receptor Agonists Salbutamol and Terbutaline Are Mediated by MKP-1. PLoS One. 2016 Feb 5;11 (2) :e0148144.|[4]Nada Choucair-Jaafar, et al. The antiallodynic action of nortriptyline and terbutaline is mediated by β (2) adrenoceptors and δ opioid receptors in the ob/ob model of diabetic polyneuropathy. Brain Res. 2014 Feb 10;1546:18-26.