NVS-ZP7-4
Product Specifications
UNSPSC Description
NVS-ZP7-4 is a Zinc transporter SLC39A7 (ZIP7) inhibitor that is also the first reported chemical tool to probe the impact of modulating ER zinc levels and investigate ZIP7 as a novel agentgable node in the Notch pathway.
Target Antigen
Others
Type
Reference compound
Related Pathways
Others
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/NVS-ZP7-4.html
Purity
98.85
Solubility
DMSO : ≥ 125 mg/mL
Smiles
O=C(NC12CCN(C[C@@H](NC3=NC4=CC=C(F)C=C4S3)CC5=CC=CC=C5)CC2)NC6=C1C=CC=C6
Molecular Weight
501.62
References & Citations
[1]Nolin E, et al. Discovery of a ZIP7 inhibitor from a Notch pathway screen. Nat Chem Biol. 2019 Feb;15(2):179-188.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, protect from light)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-114395/NVS-ZP7-4-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-114395/NVS-ZP7-4-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
2349367-89-9
Available Sizes
Curated Selection
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