M-PEG6-Lys-Mal-Toxophore-quinoline
M-PEG6-Lys-Mal-Toxophore-quinoline is a drug-linker conjugate for ADC and can be used for ADC synthesis. The payload is a NAMPT inhibitor (HY-164760) [1].
Product Specifications
CAS Number
[2369100-39-8]
UNSPSC
12352203
Target
Drug-Linker Conjugates for ADC
Type
Reference compound
Related Pathways
Antibody-drug Conjugate/ADC Related
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/m-peg6-lys-mal-toxophore-quinoline.html
Smiles
O=C1C(CC(C2=CC=C(C=C2)NC(N3CC4=CC=NC=C4C3)=O)=NN1CCCCCCNC([C@H](CCCCNC(CCOCCOCCOCCOCCOCCOC)=O)NC(CN5C(C=CC5=O)=O)=O)=O)C6=CC=CC7=C6C=CC=N7
Molecular Formula
C59H76N10O13
Molecular Weight
1133.29
References & Citations
[1]Böhnke N, et al. A Novel NAMPT Inhibitor-Based Antibody-Drug Conjugate Payload Class for Cancer Therapy. Bioconjug Chem. 2022 Jun 15;33 (6) :1210-1221.
Shipping Conditions
Room temperature
Scientific Category
ADC Related
Clinical Information
No Development Reported
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