GSK-3β inhibitor 20
GSK-3β inhibitor 20 (compound 3A) is an potent inhibitor of GSK-3β with an IC50 value of 74.4 nM[1].
Product Specifications
CAS Number
[3044109-48-7]
UNSPSC
12352211
Target
GSK-3
Type
Reference compound
Related Pathways
PI3K/Akt/mTOR; Stem Cell/Wnt
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/gsk-3β-inhibitor-20.html
Smiles
O=C(NC1=CC=CC=C1)NC2=CC(C3=CC(NN=C4NC(C(C)C)=O)=C4S3)=CC=C2
Molecular Formula
C22H21N5O2S
Molecular Weight
419.50
References & Citations
[1]Ning Yan, et al. Design, synthesis and biological evaluation of thieno[3,2-c]pyrazol-urea derivatives as potent glycogen synthase kinase 3β inhibitors based on the DFG-out conformation. Bioorg Med Chem Lett. 2024 Nov 1:112:129932.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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