VT-105
Product Specifications
UNSPSC Description
VT-105 is a potent and selective TEAD autopalmitoylation inhibitor that inhibits proliferation and tumor growth in NF2-deficient mesothelioma.
Target Antigen
Others
Type
Reference compound
Related Pathways
Others
Applications
Cancer-programmed cell death
Field of Research
cancer
Assay Protocol
https://www.medchemexpress.com/vt-105.html
Solubility
DMSO : ≥ 100 mg/mL
Smiles
C[C@@H](C1=CC=CC=N1)NC(C2=CC3=C(N=C2)C(C4=CC=C(C=C4)C(F)(F)F)=CC=C3)=O
Molecular Weight
421.41
References & Citations
[1]Tang TT, et al. Small Molecule Inhibitors of TEAD Auto-palmitoylation Selectively Inhibit Proliferation and Tumor Growth of NF2-deficient Mesothelioma. Mol Cancer Ther. 2021 Jun;20(6):986-998.
Shipping Conditions
Blue Ice
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-163644/VT-105-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-163644/VT-105-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
2417718-38-6
Available Sizes
Curated Selection
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