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Antibiofilm agent-8

Antibiofilm agent-8 (compound Ru2) enhances antimicrobial activity on visible-light exposure (400-700 nm, 10 J cm-2) . Antibiofilm agent-8 generates of oxidative stress via NADH oxidation and ROS generation and compromises bacterial wall[1].

Product Specifications

CAS Number

9007-83-4

UNSPSC

12352005

Target

Bacterial; Endogenous Metabolite; Reactive Oxygen Species (ROS)

Type

Reference compound

Related Pathways

Anti-infection; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/antibiofilm-agent-8.html

Smiles

[Cl-][Ru+2]123([N]4=C(C([N]3=CC=C5)=C5C6=C7N=CC=N6)C7=CC=C4)[N](C=CC=C8)=C8C9=[N]1C(C%10=CC=CC=[N]%102)=CC(C%11=CC=CC=C%11)=C9.F[P-](F)(F)(F)(F)F

Molecular Formula

C35H23ClF6N7PRu

Molecular Weight

823.09

References & Citations

[1]Mandal AA, et al. Visible-Light-Responsive Novel Ru (II) -Metallo-Antibiotics with Potential Antibiofilm and Antibacterial Activity. ACS Appl Mater Interfaces. 2024;16 (22) :28118-28133.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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