E-4031 (free base)
Product Specifications
UNSPSC Description
E-4031 (free base) is a selective hERG potassium channel blocker for use in class III anti-arrhythmic studies[1].
Target Antigen
Potassium Channel
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/e-4031-free-base.html
Smiles
CS(=O)(NC1=CC=C(C(C2CCN(CCC3=NC(C)=CC=C3)CC2)=O)C=C1)=O
Molecular Weight
401.52
References & Citations
[1]Daisuke Izumi, et al. Effects of bepridil versus E-4031 on transmural ventricular repolarization and inducibility of ventricular tachyarrhythmias in the dog. Pacing Clin Electrophysiol. 2010 Aug;33(8):950-9.|[2]E E Verheijck, et al. Effects of delayed rectifier current blockade by E-4031 on impulse generation in single sinoatrial nodal myocytes of the rabbit. Circ Res. 1995 Apr;76(4):607-15.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-15551A/E-4031-free-base-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-15551A/
Clinical Information
No Development Reported
CAS Number
113558-89-7
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS1387109-01 0.02 mg (E-Coli)
Recombinant Rickettsia bellii Single-stranded DNA-binding protein (ssb)
Ask
View Details MBS1387109-02 0.1 mg (E-Coli)
Recombinant Rickettsia bellii Single-stranded DNA-binding protein (ssb)
Ask
View Details MBS1387109-03 0.02 mg (Yeast)
Recombinant Rickettsia bellii Single-stranded DNA-binding protein (ssb)
Ask
View Details 
MBS1387109-04 0.1 mg (Yeast)
Recombinant Rickettsia bellii Single-stranded DNA-binding protein (ssb)
Ask
View Details