2-Fluoro-4-iodobenzonitrile

2-Fluoro-4-iodobenzonitrile is a building block, which can be used to synthesize L. infantum trypanothione reductase (Li-TryR) dimerization and oxidoreductase activity inhibitors. 2-Fluoro-4-iodo benzonitrile can also be used to synthesize transient receptor potential ankyrin 1 (TRPA1) antagonists[1].

Product Specifications

CAS Number

[137553-42-5]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Drug Intermediate

Type

Reference compound

Related Pathways

Others

Field of Research

Infection; Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/2-fluoro-4-iodobenzonitrile.html

Purity

99.97

Smiles

N#CC1=CC=C(I)C=C1F

Molecular Formula

C7H3FIN

Molecular Weight

247.01

Precautions

H302, H315, H319, H335

References & Citations

[1]Chen Q, et al. Discovery of highly potent and selective VEGFR2 kinase inhibitors for the treatment of rheumatoid arthritis. Eur J Med Chem. 2023 Sep 5;257:115456.