Alfuzosin

Alfuzosin (SL 77499-10) is an orally active, selective and competitive α1-adrenoceptor antagonist. Alfuzosin relaxes the muscles of the prostate and bladder neck, aiding in urination. Alfuzosin can be used in study of benign prostatic hyperplasia (BPH) [1][2].

Product Specifications

CAS Number

[81403-80-7]

Product Name Alternative

SL 77499

UNSPSC

12352005

Hazard Statement

H315, H319, H320

Target

Adrenergic Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Field of Research

Endocrinology

Assay Protocol

https://www.medchemexpress.com/Alfuzosin.html

Purity

99.86

Solubility

DMSO : 50 mg/mL (ultrasonic)

Smiles

O=C(C1OCCC1)NCCCN(C2=NC(N)=C3C=C(OC)C(OC)=CC3=N2)C

Molecular Formula

C19H27N5O4

Molecular Weight

389.45

Precautions

H315, H319, H320

References & Citations

[1]Martin DJ, et al. Relationship between the effects of alfuzosin on rat urethral and blood pressures and its tissue concentrations. Life Sci. 1998;63 (3) :169-76. |[2]Wilde MI, et al. Alfuzosin. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic potential in benign prostatic hyperplasia. Drugs. 1993 Mar;45 (3) :410-29.