Scillascillin

Scillascillin (compound 10) is a homoisoflavanone. Scillascillin can be isolated from S. scilloides. Scillascillin shows anticancer activity towards MCF-7 (breast cancer) and DU-145 (prostate cancer) cells with the IC50 of 9.59 and 11.32 ug/ml, respectively[1][2].

Product Specifications

CAS Number

[52706-07-7]

UNSPSC

12352005

Target

Others

Type

Natural Products

Related Pathways

Others

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/scillascillin.html

Solubility

10 mM in DMSO

Smiles

O=C1[C@]2(C3=C(C2)C=C(OCO4)C4=C3)COC5=CC(O)=CC(O)=C15

Molecular Formula

C17H12O6

Molecular Weight

312.27

References & Citations

[1]Yoichiro Nishida, et al. A new homostilbene and two new homoisoflavones from the bulbs of Scilla scilloides. Chem Pharm Bull (Tokyo) . 56, 7.|[2]Chinthala Y, et al. Anticancer Active Homoisoflavone from the Underground Bulbs of Ledebouria hyderabadensis. Pharmacognosy Res. 2014;6 (4) :303-305.