Oxaloacetic acid
Product Specifications
UNSPSC Description
Oxaloacetic acid (2-Oxosuccinic acid) is a metabolic intermediate involved in several ways, such as citric acid cycle, gluconeogenesis, the urea cycle, the glyoxylate cycle, amino acid synthesis, and fatty acid synthesis, whereby Oxaloacetic acid facilitates the clearance of reactive oxygen species (ROS) and improves mitochondrial function[1][2][3].
Target Antigen
Endogenous Metabolite; Reactive Oxygen Species
Type
Natural Products
Related Pathways
Immunology/Inflammation;Metabolic Enzyme/Protease;NF-κB
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/2-oxosuccinic-acid.html
Purity
99.88
Solubility
DMSO : ≥ 100 mg/mL|H2O : ≥ 100 mg/mL
Smiles
O=C(O)C(CC(O)=O)=O
Molecular Weight
132.07
References & Citations
[1]F. L. Breusch. The fate of oxaloacetic acid in different organs. Biochem J. 1939 Nov; 33(11): 1757-1770.|[2]Brian D Fink, et al. Oxaloacetic acid mediates ADP-dependent inhibition of mitochondrial complex II-driven respiration. J Biol Chem. 2018 Dec 21;293(51):19932-19941.|[3]Li W, et al. Oxaloacetate acid ameliorates paraquat-induced acute lung injury by alleviating oxidative stress and mitochondrial dysfunction. Front Pharmacol. 2022 Oct 13;13:1029775.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-W010382/Oxaloacetic-acid-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-W010382/Oxaloacetic-acid-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
328-42-7
Available Sizes
Curated Selection
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