(20S) -Protopanaxadiol
20S-protopanaxadiol (aPPD) is a metabolite of ginseng saponins, inhibits Akt activity and induces apoptosis in various tumor cells[1].
Product Specifications
CAS Number
30636-90-9
Product Name Alternative
20-Epiprotopanaxadiol; 20 (S) -APPD
UNSPSC
12352211
Hazard Statement
H302, H315, H319, H335
Target
Apoptosis; P-glycoprotein; Reactive Oxygen Species (ROS)
Type
Natural Products
Related Pathways
Apoptosis; Immunology/Inflammation; Membrane Transporter/Ion Channel; Metabolic Enzyme/Protease; NF-κB
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/_20S_-Protopanaxadiol.html
Concentration
10mM
Purity
99.91
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
C[C@]([C@@](C[C@H]1O)([H])[C@]2(CC[C@@H]3O)C)(CC[C@@]2([H])C3(C)C)[C@]4([C@@]1([H])[C@]([C@@](C)(O)CC/C=C(C)/C)([H])CC4)C
Molecular Formula
C30H52O3
Molecular Weight
460.73
Precautions
H302, H315, H319, H335
References & Citations
[1]iu Y, Yang G, Bu X, et al. Cell-type-specific regulation of raft-associated Akt signaling. Cell Death Dis. 2011;2 (4) :e145. Published 2011 Apr 14.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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