NLRP3-IN-18
NLRP3-IN-18 (compound 13) is a potent NLRP3 inhibitor with an IC50 value of ≤1.0 µM[1].
Product Specifications
CAS Number
[2769040-06-2]
UNSPSC
12352005
Target
NOD-like Receptor (NLR)
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/nlrp3-in-18.html
Purity
98.06
Solubility
DMSO : 5 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
ClC(C=C1)=CC=C1C2=NN=C(C3=C2C=CC=C3)NC[C@@H]4CCCO4
Molecular Formula
C19H18ClN3O
Molecular Weight
339.82
References & Citations
[1]Stéphane DORICH, et al. Pyridazine compounds for inhibiting nlrp3. WO2022216971A1.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
NLRP3
Available Sizes
Curated Selection
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